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nor-NOHA (monoacetate)
SKU
HY-112885B-10 mg
Category Reference compound
Tags Arginase, Immunology/Inflammation;Metabolic Enzyme/Protease, Metabolic Disease
$100 – $900
Products Details
Product Description
– nor-NOHA (Nω-Hydroxy-nor-L-arginine) monoacetate is a potent and selective arginase inhibitor. nor-NOHA monoacetate inhibits rat liver arginase with a Ki of 0.5 µM[1].
Web ID
– HY-112885B
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C7H16N4O5
References
– [1]Tenu JP, et al. Effects of the new arginase inhibitor N(omega)-hydroxy-nor-L-arginine on NO synthase activity in murine macrophages. Nitric Oxide. 1999;3(6):427-438.|[2]Custot J, et al. A new α-amino acid N w -hydroxy-nor-L-arginine: A highly-affinity inhibitor of arginase well adapted to bind to its manganese cluster.Journal of the American Chemical Society 119, 4086-4087(1997).
CAS Number
– 2250019-93-1
Molecular Weight
– 236.23
Compound Purity
– 99.96
SMILES
– N[C@H](C(O)=O)CCNC(NO)=N.O=C(C)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
Target
– Arginase
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
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