Products Details

Product Description

– NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM[1].

Web ID

– HY-111263

Shipping

– Room temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C18H10N2OS2

References

– [1]Kenneth T. Cheng, et al. [[5′-(4-Hydroxyphenyl)[2,2’-bithiophen]-5-yl]methylene]-propanedinitrile NIAD-4.

CAS Number

– 868592-56-7

Molecular Weight

– 334.41

SMILES

– N#C/C(C#N)=C/C1=CC=C(C2=CC=C(C3=CC=C(O)C=C3)S2)S1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Amyloid-β

Pathway

– Neuronal Signaling

Product type

– Dye Reagents

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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