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NH2-PEG6-Boc
SKU
HY-130486-100 mg
Category ADC Related
Tags ADC Linker;PROTAC Linkers, Antibody-drug Conjugate/ADC Related;PROTAC, Cancer
$30 – $50
Products Details
Product Description
– NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Web ID
– HY-130486
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H39NO8
References
– [1]Foley CA, et al. Assessing the Cell Permeability of Bivalent Chemical Degraders Using the Chloroalkane Penetration Assay. ACS Chem Biol. 2020 Jan 17;15(1):290-295.|[2]Kenneth John DIRICO, et al. Spliceostatin analogs. WO2014068443A1.
CAS Number
– 1286281-32-0
Molecular Weight
– 409.51
Compound Purity
– 97.0
SMILES
– O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCN
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker;PROTAC Linkers
Isoform
– Alkyl/ether Linkers;Non-cleavable Linker;PEG Linkers
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.