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Neoandrographolide
Price range: 109 CAD through 2,928 CAD
Products Details
Product Description
– Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iNOS and COX-2 expression through inhibiting p38 MAPKs activation.Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIAP)-overexpressing Jurkat cells, a model for chemoresistance.
Web ID
– T3884
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H40O8
Citations
– 1. Zhang J, Sun Y, Zhong L Y, et al. Structure-based discovery of neoandrographolide as a novel inhibitor of Rab5 to suppress cancer growth. Computational and Structural Biotechnology Journal. 2020, 18: 3936-3946.
2. Jiang H, Chen J, Li X, et al. Systematic Identification of Chemical Components in Fufang Shuanghua Oral Liquid and Screening of Potential Active Components Against SA¸ n Protease. Journal of Pharmaceutical and Biomedical Analysis. 2022: 115118.
3. Jiang H, Chen J, Li X, et al.Systematic identification of chemical components in Fufang Shuanghua oral liquid and screening of potential active components against SARS-CoV-2 protease.Journal of Pharmaceutical and Biomedical Analysis.2023, 223: 115118.
References
– Yang T,et al. Hypolipidemic effects of andrographolide and neoandrographolide in mice and rats. Phytother Res. 2013 Apr;27(4):618-23.
CAS Number
– 27215-14-1
Molecular Weight
– C26H40O8
Compound Purity
– 0.9852
SMILES
– C[C@@]1(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)CCC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12
Pathway
– Neuroscience|||Immunology/Inflammation
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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