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Naxagolide
$170 – $1,700
Products Details
Product Description
– Naxagolide ((+)-PHNO; Dopazinol) is a potent dopamine D2 (Dopamine Receptor) agonist. Naxagolide has the potential for the research of parkinson’s disease (PD)[1][2].
Web ID
– HY-108237
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C15H21NO2
References
– [1]G E Martin, et al. Pharmacologic profile of a novel potent direct-acting dopamine agonist, (+)-4-propyl-9-hydroxynaphthoxazine [(+)-PHNO]. J Pharmacol Exp Ther. 1984 Sep;230(3):569-76.|[2]E F Domino, et al. Relative potency and efficacy of some dopamine agonists with varying selectivities for D1 and D2 receptors in MPTP-induced hemiparkinsonian monkeys. J Pharmacol Exp Ther. 1993 Jun;265(3):1387-91.
CAS Number
– 88058-88-2
Molecular Weight
– 247.33
Compound Purity
– 99.81
SMILES
– OC1=CC2=C(C=C1)CC[C@]3([H])[C@]2([H])OCCN3CCC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 200 mg/mL (ultrasonic)
Target
– Dopamine Receptor
Isoform
– D2 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
