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MTPG
SKU
HY-101247-Get quote
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mGluR, Neurological Disease
Products Details
Product Description
– MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1].
Web ID
– HY-101247
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H11N5O2
References
– [1]Chaki S, et al. Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens. Neurosci Lett. 2006;404(1-2):182-186.|[2]Feng RF, Li WB, Liu HQ, et al. Sheng Li Xue Bao. 2003;55(3):303-310.
CAS Number
– 169209-66-9
Molecular Weight
– 233.23
SMILES
– O=C(O)C(C)(N)C1=CC=C(C2=NN=NN2)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mGluR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.