Products Details

Product Description

– MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1].

Web ID

– HY-101247

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C10H11N5O2

References

– [1]Chaki S, et al. Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens. Neurosci Lett. 2006;404(1-2):182-186.|[2]Feng RF, Li WB, Liu HQ, et al. Sheng Li Xue Bao. 2003;55(3):303-310.

CAS Number

– 169209-66-9

Molecular Weight

– 233.23

SMILES

– O=C(O)C(C)(N)C1=CC=C(C2=NN=NN2)C=C1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– mGluR

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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