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Product Description
– Mosapramine (Clospipramine) is an orally active and potent dopamine receptor antagonist with high affinity to dopamine receptor subtypes 2, 3 and 4, and with moderate affinity for the 5-HT2 receptor. Mosapramine shows antipsychotic activity and can be used in schizophrenia research[1][2].
Web ID
– HY-106584
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C28H35ClN4O
References
– [1]Takahashi N, et al. Comparison of risperidone and mosapramine addition to neuroleptic treatment in chronic schizophrenia. Neuropsychobiology. 1999;39(2):81-5.|[2]Jun Ishigooka, et al. Pilot study of plasma concentrations of mosapramine, a new iminodibenzyl antipsychotic agent, after multiple oral administration in schizophrenic patients. Current Therapeutic Research, Volume 55, Issue 3, March 1994, Pages 331-342.
CAS Number
– 89419-40-9
Molecular Weight
– 479.06
SMILES
– O=C1C2(CCN(CCCN3C4=CC(Cl)=CC=C4CCC5=C3C=CC=C5)CC2)N6C(CCCC6)N1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
