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MLKL-IN-1
SKU
HY-139878-Get quote
Category Reference compound
Tags Inflammation/Immunology, MAPK/ERK Pathway, Mixed Lineage Kinase
Products Details
Product Description
– MLKL-IN-1 is a covalent MLKL inhibitor with a KD of 50 μM.
Web ID
– HY-139878
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H20N2O3
References
– [1]Rübbelke M, et al. Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain. J Med Chem. 2021 Nov 11;64(21):15629-15638.
CAS Number
– 2837019-30-2
Molecular Weight
– 324.37
SMILES
– OC(C1=CC=C(N=C([C@@H](OC)C2=CC=C(C(C)C)C=C2)N3)C3=C1)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Mixed Lineage Kinase
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.