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Products Details
Product Description
– ML354 is a selective PAR4 antagonist with an IC50 of 140 nM[1].
Web ID
– HY-19973
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H14N2O3
References
– [1]Wen W, et al. Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4708-4713.
CAS Number
– 89159-60-4
Molecular Weight
– 282.29
SMILES
– OCC(N1C)=C(C2=CC=CC=C2)C3=C1C=CC([N+]([O-])=O)=C3
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Protease Activated Receptor (PAR)
Isoform
– PAR4
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
