ML352

$95$550

Products Details

Product Description

– ML352 is a noncompetitive inhibitor of the presynaptic choline transporter (CHT) with Ki values of 92 and 166 nM for HEK293 cells expressing human CHT and mouse forebrain synaptosomes, respectively[1].

Web ID

– HY-16934

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C21H29N3O4

References

– [1]Ennis EA, Wright J, Retzlaff CL, McManus OB, Lin Z, Huang X, et al. Identification and characterization of ML352: a novel, noncompetitive inhibitor of the presynaptic choline transporter. ACS Chem Neurosci. 2015 Mar 18;6(3):417-27.

CAS Number

– 1649450-12-3

Molecular Weight

– 387.47

Compound Purity

– 99.78

SMILES

– CC(C)C1=NOC(CNC(C2=CC(OC3CCN(C)CC3)=C(OC)C=C2)=O)=C1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– Cholinesterase (ChE)

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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