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ML233
$341 – $545
Products Details
Product Description
– ML233 is a non-peptide based potent apelin receptor (APJ) agonist (EC50=3.7 μM). ML233 displays >21-fold selective over the closely related angiotensin 1 (AT1) receptor (>79 μM)[1].
Web ID
– HY-125976
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H21NO4S
References
– [1]Khan P, et al. National Center for Biotechnology Information; 2011. Functional agonists of the apelin (APJ) receptor. In Probe Reports from the NIH Molecular Libraries Program.|[2]Pasha Khan, et al. National Center for Biotechnology Information; 2011. Functional agonists of the apelin (APJ) receptor. In Probe Reports from the NIH Molecular Libraries Program.
CAS Number
– 2080311-92-6
Molecular Weight
– 359.44
SMILES
– O=C(C(C1CCCCC1)=C/2)C=C(C)C2=N/OS(=O)(C3=CC=CC=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Apelin Receptor (APJ)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
