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Products Details
Product Description
– MJ15 is a potent and selective CB1 receptor antagonist with a Ki of 27.2 pM and an IC50 of 118.9 pM for rat CB1 receptors. MJ15 exhibits potency in obesity and hyperlipidemia models. MJ15 inhibits food intake and increases in body weight in diet-induced obese rats and mice[1].
Web ID
– HY-103327
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C23H17Cl3N4O
References
– [1]Chen W, et al. Novel selective antagonist of the cannabinoid CB1 receptor, MJ15, with prominent anti-obesity effect in rodent models. Eur J Pharmacol. 2010 Jul 10;637(1-3):178-85.
CAS Number
– 944154-76-1
Molecular Weight
– 471.77
SMILES
– O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(Cl)C=C3)=C1C)NCC4=CC=CN=C4
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Cannabinoid Receptor
Isoform
– CB1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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