Metoprolol-d7 (hydrochloride)

$125$375

Products Details

Product Description

– Metoprolol-d7 (hydrochloride) is the deuterium labeled Metoprolol. Metoprolol is an orally active, selective β1-adrenoceptor antagonist. Metoprolol shows anti-inflammation, antitumor and anti-angiogenic properties[1][2][3][4].

Web ID

– HY-17503AS

Shipping

– Room temperature

Molecular Formula

– C15H19D7ClNO3

References

– [1]Ulleryd MA, et al. Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. Biomed Res Int. 2014;2014:548783.|[2]Wang D, et al. Carvedilol has stronger anti-inflammation and anti-virus effects than metoprolol in murine model with coxsackievirus B3-induced viral myocarditis. Gene. 2014 Sep 1;547(2):195-201.|[3]Hajatbeigi B, et al. Cytotoxicity of Metoprolol on Leukemic Cells in Vitro. IJBC 2018; 10(4): 124-129.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number

– 1219798-61-4

Molecular Weight

– 310.87

SMILES

– COCCC1=CC=C(OCC(O)CNC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C=C1.[H]Cl

Clinical Information

– No Development Reported

Research Area

– Cancer; Infection; Endocrinology; Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Adrenergic Receptor;Isotope-Labeled Compounds

Isoform

– β adrenergic receptor

Pathway

– GPCR/G Protein;Neuronal Signaling;Others

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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