Metolazone-d7

$500$1,600

Products Details

Product Description

– Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.

Web ID

– HY-B0209S

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C16H9D7ClN3O3S

References

– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Stern A. Metolazone, a diuretic agent. Am Heart J. 1976 Feb;91(2):262-3.|[3]Thompson DM. A new antihypertensive: metolazone treatment of hypertension. J Kans Med Soc. 1977 Jul;78(7):337-9, 342.

CAS Number

– 2714484-71-4

Molecular Weight

– 372.88

Compound Purity

– 99.90

SMILES

– O=S(C1=CC2=C(NC(C)N(C3=C([2H])C([2H])=C([2H])C([2H])=C3C([2H])([2H])[2H])C2=O)C=C1Cl)(N)=O

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Thrombin

Pathway

– Metabolic Enzyme/Protease

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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