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Metolazone-d7
$500 – $1,600
Products Details
Product Description
– Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.
Web ID
– HY-B0209S
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H9D7ClN3O3S
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Stern A. Metolazone, a diuretic agent. Am Heart J. 1976 Feb;91(2):262-3.|[3]Thompson DM. A new antihypertensive: metolazone treatment of hypertension. J Kans Med Soc. 1977 Jul;78(7):337-9, 342.
CAS Number
– 2714484-71-4
Molecular Weight
– 372.88
Compound Purity
– 99.90
SMILES
– O=S(C1=CC2=C(NC(C)N(C3=C([2H])C([2H])=C([2H])C([2H])=C3C([2H])([2H])[2H])C2=O)C=C1Cl)(N)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Thrombin
Pathway
– Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
