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Methylprednisolone aceponate
$1,306
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Products Details
Product Description
– Methylprednisolone aceponate (ZK 91588) is a glucocorticoid and anti-inflammatory agent with weak systemic effects. Methylprednisolone aceponate is a selective glucocorticoid receptor Ligand.Methylprednisolone aceponate can be used for research of eczema and other inflammatory skin disorders[1][2][3].
Web ID
– HY-103025
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H36O7
References
– [1]Ruzicka T. Methylprednisolone aceponate in eczema and other inflammatory skin disorders — a clinical update. Int J Clin Pract. 2006 Jan;60(1):85-92. |[2]H.J. Zentel, et al. Preclinical evaluation of a new topical corticosteroid methylprednisolone aceponate. 1994. 3 (s1), S32-S38. |[3]Schäcke H, et al. Characterization of ZK 245186, a novel, selective glucocorticoid receptor agonist for the topical treatment of inflammatory skin diseases. Br J Pharmacol. 2009 Oct;158(4):1088-103.
CAS Number
– 86401-95-8
Molecular Weight
– 472.57
SMILES
– CC(OCC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C([C@@H](C)C3)=CC(C=C4)=O)C)([H])[C@@H](O)C2)([H])CC1)C)OC(CC)=O)=O)=O
Clinical Information
– Phase 4
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Glucocorticoid Receptor
Pathway
– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
