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Methotrexate metabolite
SKU
HY-108251-10 mg
Category Reference compound
Tags Antifolate;Drug Metabolite, Cell Cycle/DNA Damage;Metabolic Enzyme/Protease, Inflammation/Immunology
$32 – $160
Products Details
Product Description
– Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent[1].
Web ID
– HY-108251
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C15H15N7O2
References
– [1]Schofield RC, et al. Development and validation of a turbulent flow chromatography and tandem mass spectrometry method for the quantitation of methotrexate and its metabolites 7-hydroxy methotrexate and DAMPA in serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:169-75.
CAS Number
– 19741-14-1
Molecular Weight
– 325.33
Compound Purity
– 98.22
SMILES
– O=C(O)C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Antifolate;Drug Metabolite
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.