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Meloxicam
SKU
HY-B0261-100 mg
Category Reference compound
Tags Apoptosis;Autophagy;COX;MMP, Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease, Inflammation/Immunology; Cancer
$40 – $100
Products Details
Product Description
– Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively.
Web ID
– HY-B0261
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C14H13N3O4S2
References
– [1]Lazer ES, et al. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40(6):980-9.|[2]Iturriaga MP, et al. Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells. Oncol Lett. 2017 Aug;14(2):2198-2206.|[3]Fikry EM, et al. Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity. J Biochem Mol Toxicol. 2018 Feb;32(2).
CAS Number
– 71125-38-7
Molecular Weight
– 351.40
Compound Purity
– 99.70
SMILES
– O=C(C1=C(O)C2=CC=CC=C2S(N1C)(=O)=O)NC3=NC=C(C)S3
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 0.67 mg/mL (ultrasonic)
Target
– Apoptosis;Autophagy;COX;MMP
Isoform
– COX-1;COX-2;MMP-2
Pathway
– Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.