Meloxicam

$40$100

Products Details

Product Description

– Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively.

Web ID

– HY-B0261

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C14H13N3O4S2

References

– [1]Lazer ES, et al. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40(6):980-9.|[2]Iturriaga MP, et al. Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells. Oncol Lett. 2017 Aug;14(2):2198-2206.|[3]Fikry EM, et al. Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity. J Biochem Mol Toxicol. 2018 Feb;32(2).

CAS Number

– 71125-38-7

Molecular Weight

– 351.40

Compound Purity

– 99.70

SMILES

– O=C(C1=C(O)C2=CC=CC=C2S(N1C)(=O)=O)NC3=NC=C(C)S3

Clinical Information

– Launched

Research Area

– Inflammation/Immunology; Cancer

Solubility

– DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 0.67 mg/mL (ultrasonic)

Target

– Apoptosis;Autophagy;COX;MMP

Isoform

– COX-1;COX-2;MMP-2

Pathway

– Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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