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MELK-8a (hydrochloride)
$180 – $2,520
Products Details
Product Description
– MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM.
Web ID
– HY-100368A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H33ClN6O
References
Р[1]Tour̩ BB, et al. Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight. J Med Chem. 2016 May 26;59(10):4711-23.
CAS Number
– 2096992-20-8
Molecular Weight
– 469.02
Compound Purity
– 99.26
SMILES
– CN(CC1)CCN1C2=CC=C(N3C=C(C4=CC=NC=C4OCC5CCNCC5)C=N3)C=C2.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 8.6 mg/mL (ultrasonic;warming)|H2O : ≥ 100 mg/mL
Target
– MELK
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
