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Product Description
– Mcl-1 inhibitor 9 (example 2) is a myeloid cell leukemia 1 (Mcl-1) inhibitor with IC50 value of 0.21889 nM. Mcl-1 inhibitor 9 shows anti-tumor activity[1].
Web ID
– HY-148203
Shipping
– Room temperature
Molecular Formula
– C32H39ClN2O5S
References
– [1]Sean P. Brown, et al. Tetrahydronaphthalene derivatives that inhibit mcl-1 protein. WO2016033486A1.
CAS Number
– 1883727-31-8
Molecular Weight
– 599.18
SMILES
– ClC1=CC=C([C@@]2(CCC3)CN4C5=CC(C(NS(=O)([C@@H]([C@H](C/C=C[C@@H]([C@@]6([H])[C@](CC6)([H])C4)O)C)C)=O)=O)=CC=C5OC2)C3=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
