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MCC-Modified Daunorubicinol

Products Details

Product Description

– Daunorubicinol is a agent-linker conjugate for ADC with potent antitumor activity by using Aur0101 (DNA Topoisomerase II inhibitor), linked via the ADC linker[1].

Web ID

– HY-128959

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C39H44N4O13

References

– [1]Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.

CAS Number

– 721945-30-8

Molecular Weight

– 776.79

SMILES

– N[C@H]([C@H](O)[C@H](C)O1)C[C@]1([H])O[C@@H]2C3=C(C[C@](/C(CO)=N/NC(C4CCC(CN5C(C=CC5=O)=O)CC4)=O)(O)C2)C(O)=C6C(C(C7=C(OC)C=CC=C7C6=O)=O)=C3O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Drug-Linker Conjugates for ADC

Isoform

– Daunorubicins/Doxorubicins

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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