Mc-Dexamethasone

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Products Details

Product Description

– Mc-Dexamethasone is a agent-linker conjugate for ADC. Mc-Dexamethasone is made toxin Dexamethasone (HY-14648) conjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist.

Web ID

– HY-136290

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C29H38FN3O6

References

– [1]LaLone CA, et al. Effects of a glucocorticoid receptor agonist, Dexamethasone, on fathead minnow reproduction, growth, and development. Environ Toxicol Chem. 2012 Mar;31(3):611-22.

CAS Number

– 1618096-56-2

Molecular Weight

– 543.63

SMILES

– C[C@]([C@](O)1/C(CO)=N/NCCCN(C2=O)C(C=C2)=O)(C[C@@H]3O)[C@](C[C@H]1C)([H])[C@@](CCC4=CC5=O)([H])[C@]3([C@]4(C=C5)C)F

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Drug-Linker Conjugates for ADC

Isoform

– Maytansinoids

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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