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Products Details
Product Description
– Mc-Dexamethasone is a agent-linker conjugate for ADC. Mc-Dexamethasone is made toxin Dexamethasone (HY-14648) conjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist.
Web ID
– HY-136290
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H38FN3O6
References
– [1]LaLone CA, et al. Effects of a glucocorticoid receptor agonist, Dexamethasone, on fathead minnow reproduction, growth, and development. Environ Toxicol Chem. 2012 Mar;31(3):611-22.
CAS Number
– 1618096-56-2
Molecular Weight
– 543.63
SMILES
– C[C@]([C@](O)1/C(CO)=N/NCCCN(C2=O)C(C=C2)=O)(C[C@@H]3O)[C@](C[C@H]1C)([H])[C@@](CCC4=CC5=O)([H])[C@]3([C@]4(C=C5)C)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Drug-Linker Conjugates for ADC
Isoform
– Maytansinoids
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
