Mavelertinib
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Mavelertinib

SKU T21322-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 98 CAD through 362 CAD

Products Details

Product Description

– Mavelertinib (PF-06747775) is an orally available, selective and potent EGFR tyrosine kinase (EGFR TKI) inhibitor with inhibitory effects on T790M/L858R and T790M/Del, and can be used in the study of oncology and respiratory diseases.

Web ID

– T21322

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H22FN9O2

References

– Planken S, et, al. Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Onc

CAS Number

– 1776112-90-3

Molecular Weight

– C18H22FN9O2

Compound Purity

– 1

SMILES

– COc1nn(C)cc1Nc1nc(nc2n(C)cnc12)N1C[C@@H](F)[C@@H](C1)NC(=O)C=C

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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