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Products Details
Product Description
– MAT2A-IN-2 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-2 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2020243376A1, compound 172)[1].
Web ID
– HY-142929
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H17F3N6O2
References
– [1]Zenon D. Konteatis, et al. Heterobicyclic inhibitors of mat2a and methods of use for treating cancer. Patent WO2020243376A1.
CAS Number
– 2565671-21-6
Molecular Weight
– 466.42
SMILES
– O=C1C(C2=CN3C=CN=C3C=C2)=CC4=C(N1C5=CC=C(C=C5)OC)N=C(NCC(F)(F)F)N=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Somatostatin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
