MARK4 inhibitor 2

SKU HY-154986-10 mg Category Tags , ,

$390$2,000

Products Details

Product Description

– MARK4 inhibitor 2 is an inhibitor of microtubule affinity-regulating kinase 4 (MARK4) with an Km of 6.3×10 7 and an IC50 of 0.82 μM. MARK4 inhibitor 2 inhibits the growth of human cells and can be used for cancer research[1].

Web ID

– HY-154986

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-Kinase/protease

Molecular Formula

– C34H30N4O3

References

– [1]Maria Voura, et.al. Synthesis, Structural Modification, and Bioactivity Evaluation of Substituted Acridones as Potent Microtubule Affinity-Regulating Kinase 4 InhibitorsACS Pharmacology & Translational Science 2023 6 (7), 1052-1074.

Molecular Weight

– 542.63

Compound Purity

– 99.47

SMILES

– O=C(NC1=CC=C(C)C=C1)[C@@H](NC(CN(C2=C3C=CC=C2)C4=CC=C(C)C=C4C3=O)=O)CC5=CNC6=C5C=CC=C6

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– AMPK

Pathway

– Epigenetics;PI3K/Akt/mTOR

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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