Mal-PEG8-Val-Ala-PAB-Exatecan

$550$2,400

Products Details

Product Description

– Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research[1].

Web ID

– HY-147271

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture and light)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C66H85FN8O20

References

– [1]Manel KRAIEM. Treatment of cancer. WO2021151984A1.

CAS Number

– 2679821-39-5

Molecular Weight

– 1329.42

Compound Purity

– 98.75

SMILES

– O=C(CCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O.[7]

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Drug-Linker Conjugates for ADC

Isoform

– Protease Cleavable Linker

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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