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Mal-PEG8-Val-Ala-PAB-Exatecan
$550 – $2,400
Products Details
Product Description
– Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research[1].
Web ID
– HY-147271
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C66H85FN8O20
References
– [1]Manel KRAIEM. Treatment of cancer. WO2021151984A1.
CAS Number
– 2679821-39-5
Molecular Weight
– 1329.42
Compound Purity
– 98.75
SMILES
– O=C(CCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O.[7]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Drug-Linker Conjugates for ADC
Isoform
– Protease Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
