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Mal-amide-PEG8-Val-Ala-PAB-PNP
SKU
HY-148425-100 mg
Category ADC Related
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Cancer
$720 – $2,000
Products Details
Product Description
– Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-148425
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C48H68N6O19
References
– [1]Junutula JR, et, al. Preparation of isoquinolidinobenzodiazepines and antibody conjugates thereof for treatment of hematological malignancies and solid tumors. WO2018053552
CAS Number
– 2210247-59-7
Molecular Weight
– 1033.08
Compound Purity
– 99.60
SMILES
– O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)N[C@@H](C(C)C)C(N[C@@H](C)C(NC2=CC=C(C=C2)COC(OC3=CC=C(C=C3)[N+]([O-])=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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