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M443
Price range: 318 CAD through 602 CAD
Products Details
Product Description
– M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.
Web ID
– T15943
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C31H30F3N7O2
References
– Markowitz D, et al. Pharmacological Inhibition of the Protein Kinase MRK/ZAK Radiosensitizes Medulloblastoma. Mol Cancer Ther. 2016 Aug;15(8):1799-808.
CAS Number
– 1820684-31-8
Molecular Weight
– C31H30F3N7O2
Compound Purity
– 0.9895
SMILES
– Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)C3CCCN(C3)C(=O)C=C)c2)cc(c1)C(F)(F)F
Target
– mTOR|||PI3K
Pathway
– MAPK|||Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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