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Lyn peptide inhibitor
595 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Cell-permeable inhibitor of Lyn-dependent effects of the IL-5 receptor. Blocks binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors, blocking Lyn activation. Inhibits IL-5 receptor-mediated eosinophil differentiation and survival in vitro. Inhibits airway eosinophilic inflammation in mouse model of asthma.
Web ID
– TP2008
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C115H184N30O24
References
– Adachi et al (1999) The mapping of the Lyn kinase binding site of the common β subunit of IL-3/granulocyte-macrophage colony-stimulating factor/IL-5 receptor. J.Immunol. 162 1496 PMID:
CAS Number
– 222018-18-0
Molecular Weight
– C115H184N30O24
SMILES
– C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC(CNC([C@H](CC2=CC=C(O)C=C2)NC(CCCCCCCCCCCCCCCCC)=O)=O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(=O)N4[C@H](C(N)=O)CCC4)CC(N)=O)=O)CCC3)[C@H](CC)C)=O)CCCCN)=O)CCC(O)=O)=O)CCC(O)=O)=O)C=5C=6C(NC5)=CC=CC6
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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