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LXH254
Price range: 77 CAD through 2,432 CAD
Products Details
Product Description
– LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.
Web ID
– T11898
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H25F3N4O4
Citations
– 1. Li W, Shi X, Tan C, et al.Plasma membrane-associated ARAF condensates fuel RAS-related cancer drug resistance.Nature Chemical Biology.2025: 1-12.
References
– CAPONIGRO, Giordano, et al. THERAPEUTIC COMBINATIONS COMPRISING A RAF INHIBITOR AND A ERK INHIBITOR. WO 2018051306 A1 20180322
CAS Number
– 1800398-38-2
Molecular Weight
– C25H25F3N4O4
Compound Purity
– 0.9931
SMILES
– Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1cc(OCCO)nc(c1)N1CCOCC1
Target
– ADC Linker
Pathway
– MAPK
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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