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Products Details
Product Description
– LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor. LSD1-IN-15 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC50 values of 0.149, 0.028, and 0.327 μM, respectively. LSD1-IN-15 displays cell growth arrest in prostate cancer LNCaP cells, with an IC50 of 9.9 μM[1].
Web ID
– HY-144756
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H20N2O
References
– [1]Fioravanti R, et al. Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. J Enzyme Inhib Med Chem. 2022 Dec;37(1):973-985.
Molecular Weight
– 328.41
SMILES
– NC1CC1C2=CC=C(C=C2)NC(C3=CC=CC(C4=CC=CC=C4)=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Demethylase;Monoamine Oxidase
Isoform
– KDM1/LSD1;MAO-A;MAO-B
Pathway
– Epigenetics;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
