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Products Details
Product Description
– LSD1-IN-12 (compound 2) is a potent LSD1 inhibitor, with Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B), respectively[1].
Web ID
– HY-144673
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H16N2O
References
– [1]Li C, et al. Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors. J Med Chem. 2022 Mar 10;65(5):4335-4349.
CAS Number
– 1228143-76-7
Molecular Weight
– 252.31
SMILES
– N[C@@H]1C[C@H]1C2=CC=C(C=C2)NC(C3=CC=CC=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Demethylase;Monoamine Oxidase
Isoform
– KDM1/LSD1;MAO-A;MAO-B
Pathway
– Epigenetics;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
