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Products Details
Product Description
– Lp-PLA2-IN-14 (Compound 19) is an Lp-PLA2 inhibitor with a pIC50 of 8.4 against rhLp-PLA2. Lp-PLA2-IN-14 can be used for the research of neurodegenerative related diseases, such as Alzheimer Disease (AD), glaucoma, age-related macular degeneration (AMD) or cardiovascular diseases including atherosclerosis and the like[1].
Web ID
– HY-153560
Shipping
– Room temperature
Molecular Formula
– C16H14F3N3O3
References
– [1]Zhenghua Gu, et al. Tricyclic pyrimidone compounds, preparation method, composition and application thereof. Patent CN113861220A.
CAS Number
– 2756855-66-8
Molecular Weight
– 353.30
SMILES
– O=C1N=C(C2=C(N1CCC3)N3CCO2)OCC4=CC(F)=C(C(F)=C4)F
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Phospholipase
Isoform
– Phospholipase A
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
