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Products Details
Product Description
– Lipoxin A4 (LXA4) is a lipoxygenase-derived arachidonate-like mediator with anti-inflammatory properties.Lipoxin A4 attenuates MSU crystal-induced NLRP3 inflammasome activation through inhibition of Nrf2, and regulates M1/M2 macrophage polarization through the FPR2-IRF pathway.Lipoxin inhibits oxidative stress and inflammation.
Web ID
– T36051
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H32O5
References
– Hu F, et al. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes associated with the ERK1/2 and NF-κB pathways. J Dermatol Sci. 2015 Jun;78(3):181-8.
CAS Number
– 89663-86-5
Molecular Weight
– C20H32O5
Compound Purity
– 0.95
SMILES
– [C@H]([C@H](CCCC(O)=O)O)(/C=C/C=C/C=CC=C[C@H](CCCCC)O)O
Pathway
– Metabolism|||Immunology/Inflammation
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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