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Lenalidomide-Br
46 CAD
Products Details
Product Description
– Lenalidomide-Br (Compound 41), a derivative of Lenalidomide, acts as a ligand for cereblon (CRBN) – an E3 ubiquitin ligase involved in protein recruitment. This compound can be conjugated to a protein ligand via a linker to create PROTACs, such as the PROTAC STAT3 degrader SD-36.
Web ID
– T18064
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H11BrN2O3
References
– Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.
CAS Number
– 2093387-36-9
Molecular Weight
– C13H11BrN2O3
Compound Purity
– 0.9837
SMILES
– O=C1N(CC=2C1=CC=CC2Br)C3C(=O)NC(=O)CC3
Target
– Others
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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