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LC3-mHTT-IN-AN1
Price range: 56 CAD through 1,229 CAD
Products Details
Product Description
– LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
Web ID
– T8081
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H9Br2NO3
References
– Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Nov;575(7781):203-209.
CAS Number
– 486443-73-6
Molecular Weight
– C15H9Br2NO3
Compound Purity
– 0.9726
SMILES
– Oc1cc(C=C2/C(=O)Nc3ccc(Br)cc23)cc(Br)c1O
Pathway
– PROTAC|||Autophagy
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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