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LC-PEG8-SPDP
SKU
HY-126497-Get quote
Category ADC Related
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Cancer
Products Details
Product Description
– LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
Web ID
– HY-126497
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C31H49N3O13S2
References
– [1]Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54(10):3606-23.
CAS Number
– 1252257-56-9
Molecular Weight
– 735.86
SMILES
– O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCSSC2=NC=CC=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Cleavable Linker;Disulfide Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.