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Lanicemine (dihydrochloride)
$60 – $550
Products Details
Product Description
– Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1].
Web ID
– HY-108235A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C13H16Cl2N2
References
– [1]Sanacora G, et al. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacywith minimal psychotomimetic adverse effects. Mol Psychiatry. 2014 Sep;19(9):978-85.
CAS Number
– 153322-06-6
Molecular Weight
– 271.19
Compound Purity
– 99.94
SMILES
– N[C@H](C1=CC=CC=C1)CC2=CC=CC=N2.Cl.Cl
Clinical Information
– Phase 2
Research Area
– Neurological Disease
Solubility
– DMSO : 240 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
Target
– iGluR
Isoform
– NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
