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Lactate transportor 1
SKU
HY-155382-Get quote
Category Reference compound
Tags Cancer; Others, Membrane Transporter/Ion Channel, Monocarboxylate Transporter
Products Details
Product Description
– Lactate transportor 1 (compound 1) is an active lactate transporter in living cells. Lactate transportor 1 displays the cytotoxic effect, with IC50 values of 3.36, 3.27,5.58 and 7.66 μM in Hela, CAL27, MCF7 and MCF10A, respectively. Lactate transportor 1 has an additive effect with Cisplatin (HY-17394) observed in HeLa cells[1].
Web ID
– HY-155382
Shipping
– Room temperature
Molecular Formula
– C28H36ClN5O
References
– [1]Alonso-Carrillo D, et al. Small molecule anion carriers facilitate lactate transport in model liposomes and cells. iScience. 2023;26(10):107898. Published 2023 Sep 14.
Molecular Weight
– 494.07
SMILES
– CC(C)(C)C1=CC=C(N2N=NC(C3=CC(OC)=C(/C=[NH+]/C4(C[C@@H](C5)C6)C[C@H]5C[C@H]6C4)N3)=C2)C=C1.[Cl-]
Clinical Information
– No Development Reported
Research Area
– Cancer; Others
Solubility
– 10 mM in DMSO
Target
– Monocarboxylate Transporter
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.