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Products Details
Product Description
– Lactate transportor 1 (compound 1) is an active lactate transporter in living cells. Lactate transportor 1 displays the cytotoxic effect, with IC50 values of 3.36, 3.27,5.58 and 7.66 μM in Hela, CAL27, MCF7 and MCF10A, respectively. Lactate transportor 1 has an additive effect with Cisplatin (HY-17394) observed in HeLa cells[1].
Web ID
– HY-155382
Shipping
– Room temperature
Molecular Formula
– C28H36ClN5O
References
– [1]Alonso-Carrillo D, et al. Small molecule anion carriers facilitate lactate transport in model liposomes and cells. iScience. 2023;26(10):107898. Published 2023 Sep 14.
Molecular Weight
– 494.07
SMILES
– CC(C)(C)C1=CC=C(N2N=NC(C3=CC(OC)=C(/C=[NH+]/C4(C[C@@H](C5)C6)C[C@H]5C[C@H]6C4)N3)=C2)C=C1.[Cl-]
Clinical Information
– No Development Reported
Research Area
– Cancer; Others
Solubility
– 10 mM in DMSO
Target
– Monocarboxylate Transporter
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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