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Products Details
Product Description
– KTX-582 is a potent IRAK4 degrader with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. It effectively induces apoptosis in MYD88 MT DLBCL and has demonstrated efficacy in inducing in vivo tumor regressions in a lymphoma model [1] [2] [3].
Web ID
– T74664
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C45H51F3N8O7
CAS Number
– 2573298-13-0
Molecular Weight
– C45H51F3N8O7
SMILES
– CN(CCCO[C@H]1C[C@@H](C1)Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)C[C@H]1CC[C@@H](CC1)n1cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(cc2n1)C(C)(C)O
Pathway
– PROTAC
Product type
– PROTAC
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