KRAS G12D inhibitor 17

SKU T74663-5 mg Category Brand:

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Products Details

Product Description

– KRAS G12D Inhibitor 17 (example 8), a quinazoline-linked (4R)-4-hydroxy-L-prolinamide compound, acts as a proteolysis targeting chimera (PROTAC) [1], specifically inducing degradation of the G12D-mutation KRAS protein.

Web ID

– T74663

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C60H65FN12O7S

CAS Number

– 2821793-99-9

Molecular Weight

– C60H65FN12O7S

SMILES

– [H][C@]12CN(c3nc(OC4CCOCC4)nc4c(OCc5ccc(cc5)-c5cn(nn5)[C@@H](C(C)C)C(=O)N5C[C@H](O)C[C@H]5C(=O)N[C@@H](CO)c5ccc(cc5)-c5scnc5C)c(c(cc34)C3CC3)-c3c(C)c(F)cc4[nH]ncc34)[C@]([H])(CN1)C2

Pathway

– Others

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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