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Products Details
Product Description
– Ketotrexate sodium is an orally active antifolate and immunosuppressant. Ketotrexate sodium has good anti-inflammatory activity and is widely used in rheumatoid arthritis (RA). Ketotrexate sodium is used in research into cancer and autoimmune diseases[1][2].
Web ID
– HY-105934A
Shipping
– Room temperature
Molecular Formula
– C21H25N7Na2O6
References
– [1]Puig L. Methotrexate: new therapeutic approaches. Actas Dermosifiliogr. 2014 Jul-Aug;105(6):583-9. |[2]Torres RP, et al. Methotrexate: Implications of pharmacogenetics in the treatment of patients with Rheumatoid Arthritis. ARP Rheumatol. 2022 Oct 1;1(3):225-229.
CAS Number
– 52386-42-2
Molecular Weight
– 517.45
SMILES
– O=C(CC[C@H](NC(C1=CC=C(C=C1)NCCC2N(C3=C(NC2)NC(N)=NC3=O)C)=O)C(O[Na])=O)O[Na]
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Antifolate
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
