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KCNQ1 activator-1
SKU
HY-145992-10 mg
Category Reference compound
Tags Cardiovascular Disease, Membrane Transporter/Ion Channel, Potassium Channel
$480 – $1,440
Products Details
Product Description
– KCNQ1 activator-1 (compound 3) is a potent activator of KCNQ1 channel. KCNQ1 activator-1 has the potential for the research of long QT syndrome (LQTS)[1].
Web ID
– HY-145992
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H23N3O4S2
References
– [1]Mattmann ME, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941.
CAS Number
– 1008671-38-2
Molecular Weight
– 457.57
Compound Purity
– 99.03
SMILES
– O=C(C1N(S(=O)(C2=CC=CC=C2)=O)CCCC1)NC3=NC(C4=CC=C(OC)C=C4)=CS3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.