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K-Ras ligand-Linker Conjugate 5
136 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– K-Ras ligand-Linker Conjugate 5 is a chemical compound combining a K-Ras recruiting ligand with a PROTAC linker for E3 ligases, such as VHL, CRBN, MDM2, and IAP. This conjugate is crucial for synthesizing PROTAC K-Ras Degrader-1, displaying a degradation efficacy of ≥70% in SW1573 cells [1].
Web ID
– T18058
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C42H59N7O8
References
– CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.
CAS Number
– 2378261-85-7
Molecular Weight
– C42H59N7O8
SMILES
– CN1C[C@@H](C[C@H]1COc1nc2CN(CCc2c(n1)N1CCN([C@@H](CC#N)C1)C(=O)OC(C)(C)C)c1cccc2ccccc12)OCCOCCOCCOCCO
Target
– Others
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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