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Products Details
Product Description
– JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)
Web ID
– T5443
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H17ClN4O2S
Citations
– 1. Zhao L, Zhu Y, Tao H, et al.Ailanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation.Acta Pharmaceutica Sinica B.2024
References
– Rosner M , Hengstschl?Ger M . Targeting Epigenetic Readers in Cancer[J]. New England Journal of Medicine, 2012, 367(18):1764-1765.
CAS Number
– 202592-23-2
Molecular Weight
– C19H17ClN4O2S
Compound Purity
– 0.999
SMILES
– CC=1C2=C(N3C([C@H](CC(O)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C)SC1C
Pathway
– Chromatin/Epigenetic
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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