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Products Details
Product Description
– JAK1-IN-11 (compound 11) is a potent inhibitor of JAK，with IC50s of 0.02 nM (JAK1)，and 0.44 nM (JAK2)，respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1].
Web ID
– HY-153568
Shipping
– Room temperature
Molecular Formula
– C26H36N6O4S
References
– [1]Shen W. et al. Amide or sulfonamide substituted hydrazine derivative applied as JAK kinase inhibitor. China, CN110724142 A. 2020-01-24.
CAS Number
– 2427608-43-1
Molecular Weight
– 528.67
SMILES
– C[C@@H](O)C1=NC2=CNC3=NC=CC3=C2N1N(CC4)CCC4CNS(C[C@@]56C(C)(C)[C@@](CC6)([H])CC5=O)(=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
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