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JAK-IN-14
$230 – $1,900
Products Details
Product Description
– JAK-IN-14 is a potent and selective JAK1 inhibitor, with an IC50 of 8-fold more selective for JAK1 than JAK2 and JAK3 (Patent WO2016119700A1, compound 16)[1].
Web ID
– HY-139807
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H15FN4O
References
– [1]Jin Li, et al. Substituted imidazo [1, 2-a] pyridin-2-ylamine compounds, and pharmaceutical compositions and methods of use thereof. WO2016119700A1.
CAS Number
– 1973485-06-1
Molecular Weight
– 334.35
Compound Purity
– 98.72
SMILES
– N#CCC1=CC(F)=C(C2=CC=CC3=NC(NC(C4CC4)=O)=CN32)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 10.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
