Indoximod
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Indoximod

SKU T6543-1 g Category Brand:

Price range: 64 CAD through 142 CAD

Products Details

Product Description

– Indoximod (NLG-8189) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.

Web ID

– T6543

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C12H14N2O2

Citations

– 1. Nguyen D J M, Theodoropoulos G, Li Y Y, et al. Targeting the kynurenine pathway for the treatment of cisplatin resistant lung cancer. Molecular Cancer Research. 2019: molcanres. 0239.2019

References

– Hou DY, et al. Cancer Res. 2007, 67(2), 792-801.

CAS Number

– 110117-83-4

Molecular Weight

– C12H14N2O2

Compound Purity

– 0.995

SMILES

– Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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