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IMT1B
Price range: 237 CAD through 2,224 CAD
Products Details
Product Description
– IMT1B (LDC203974) is an orally administered, specific noncompetitive allosteric inhibitor of mitochondrial RNA polymerase (POLRMT), effectively suppressing mitochondrial DNA (mtDNA) expression and conferring anti-tumor properties.
Web ID
– T8842
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H21ClFNO6
References
– Nina A Bonekamp, et al. Small-molecule inhibitors of human mitochondrial DNA transcription. Nature. 2020 Dec;588(7839):712-716.
CAS Number
– 2304621-06-3
Molecular Weight
– C24H21ClFNO6
Compound Purity
– 0.9826
SMILES
– C[C@@H](Oc1ccc2c(cc(=O)oc2c1)-c1ccc(F)cc1Cl)C(=O)N1CCC[C@@H](C1)C(O)=O
Pathway
– DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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