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Products Details
Product Description
– (-)-Ibuprofenamide is an amide proagent of Ibuprofen with anti-inflammatory activity[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[2].
Web ID
– HY-111950
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H19NO
References
– [1]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.|[2]Shanbhag VR, et al. Ester and amide prodrugs of ibuprofen and naproxen: synthesis, anti-inflammatory activity, and gastrointestinal toxicity. J Pharm Sci. 1992 Feb;81(2):149-54.
CAS Number
– 121839-78-9
Molecular Weight
– 205.30
SMILES
– CC(C)CC1=CC=C([C@@H](C)C(N)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
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