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HQNO
$64 – $550
Products Details
Product Description
– HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2].
Web ID
– HY-130055
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H21NO2
References
– [1]N J Jacobs, et al. Evidence for Involvement of the Electron Transport System at a Late Step of Anaerobic Microbial Heme Synthesis. Biochim Biophys Acta. 1977 Jan 6;459(1):141-4.|[2]Jessica Petri, et al. Structure of the NDH-2 – HQNO Inhibited Complex Provides Molecular Insight Into Quinone-Binding Site Inhibitors. Biochim Biophys Acta Bioenerg. 2018 Jul;1859(7):482-490.
CAS Number
– 341-88-8
Molecular Weight
– 259.34
Compound Purity
– 99.14
SMILES
– OC(C1=C2C=CC=C1)=CC(CCCCCCC)=N2=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Mitochondrial Metabolism
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
