HQNO

$64$550

Products Details

Product Description

– HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2].

Web ID

– HY-130055

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C16H21NO2

References

– [1]N J Jacobs, et al. Evidence for Involvement of the Electron Transport System at a Late Step of Anaerobic Microbial Heme Synthesis. Biochim Biophys Acta. 1977 Jan 6;459(1):141-4.|[2]Jessica Petri, et al. Structure of the NDH-2 – HQNO Inhibited Complex Provides Molecular Insight Into Quinone-Binding Site Inhibitors. Biochim Biophys Acta Bioenerg. 2018 Jul;1859(7):482-490.

CAS Number

– 341-88-8

Molecular Weight

– 259.34

Compound Purity

– 99.14

SMILES

– OC(C1=C2C=CC=C1)=CC(CCCCCCC)=N2=O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Mitochondrial Metabolism

Pathway

– Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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